WEIGHT LOSS

5-AMINO-1MQ

What is 5-AMINO-1MQ?

5-AMINO-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-AMINO-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as ‘the longevity gene’ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.

IN OTHER WORDS…

5-AMINO-1MQ allows your body to burn fat for energy while maintaining muscle mass preferentially. 5-AMINO-1MQ is both safe and effective for reversing and preventing diet-induced obesity. It is a potentially superior treatment option for individuals suffering from (or who are at risk for) Type 2 Diabetes and other metabolic comorbidities to obesity. Furthermore, the activation of SIRT1 by an increase in NAD+ suggests 5-AMINO-1MQ is a good option for patients who are looking to develop a comprehensive anti-aging protocol.

WHAT YOU NEED TO KNOW:

5-AMINO-1MQ blocks an enzyme that plays a role in energy utilization. It functions to actively increase the basal metabolic rate (BMR). This increase in BMR is often accompanied by an increase in appetite. For 5-AMINO-1MQ to work most effectively for fat loss, patients taking the drug should continue to operate at a caloric deficit, which means you consume fewer calories than you burn. Furthermore, patients can expect to see improved physical performance approximately 2 weeks after starting the medication.

Are there other forms of 5-AMINO-1MQ available?

5-AMINO-1MQ is available as an oral capsule dosed multiple times daily for a given period of time.

CJC 1295/Ipamorelin

WHAT IS CJC 1295/IPAMORELIN?

• CJC 1295 is prescribed as a Growth Hormone Releasing Hormone (GHRH) analog that acts on the pituitary gland
• Ipamorelin is prescribed as a selective Growth Hormone Secretagogue that also acts on the pituitary gland
• These two combinations can act together to increase Human Growth Hormone by acting on 2 different families of receptors
• CJC 1295/Ipamorelin is normally prescribed at night to maximize the body’s natural cycle of growth hormone and stimulate the pituitary gland during REM sleep.

WHY WOULD I WANT TO USE CJC 1295/IPAMORELIN?

The increased volume of Human Growth Hormone (hGH) produced by the pituitary gland have shown to cause an increase in the production of Insulin-like Growth Factor-1 (IGF-1) by the liver and can possibly result in several health benefits such as:

• Decreased body fat
• Increased muscle mass
• Increased strength
• Improved energy & strength
• Improved quality of sleep
• Shown to help combat insomnia
• Increased physical and mental performance
• Enhanced calcium retention
• Improved bone density
• Improved immune function
• Improved fat burning
• Improved skin elasticity
• Shown to aid in connective tissue repair post injury

WHAT YOU NEED TO KNOW:

1. It is best prescribed to be taken before bed on an empty stomach
2. CJC 1295/Ipamorelin should not be used while pregnant or breastfeeding
3. Always tell your physician about all medications and supplements, especially corticosteroids and thyroid medications, that you are taking
4. Common side effects of CJC 1295/Ipamorelin include reactions at the injection site, such as pain, redness or swelling, along with flushing of the face; and less than 1% of patients report dizziness, headache or hyperactivity.

Benefits for patients on CJC 1295/Ipamorelin shown over the first 6 weeks of protocol may include improvements in: